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Specimen Collection Manual and Test Catalog

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WEST NILE VIRUS ANTIBODIES (IGG, IGM), CSF

Geisinger Epic Procedure Code:  LAB5244    Geisinger Epic ID:  207317

SPECIMEN COLLECTION
Specimen type: 

CSF


Preferred collection container: 
Specimen required: 

2 mL CSF, minimum 0.7 mL


Special notes: 

Collect in sterile container 



SPECIMEN PROCESSING
Processing instructions: 

Do not centrifuge. Aliquot and deliver to Referred Testing


Transport temperature: 

Refrigerated 


Specimen stability: 

Room temperature: 4 days. Refrigerated: 7 days. Frozen: 30 days.


Rejection criteria: 

Gross hemolysis • Grossly icteric



TEST DETAILS
CPT code(s):  86788, 86789
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

West Nile Virus Ab (IgG), CSF; West Nile Virus Ab (IgM), CSF


Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

Quest Test Code 36597; WNVCSF


Clinical significance: 

West Nile Virus Antibodies (IgG, IgM), CSF - The West Nile Virus (WNV) is a single-stranded RNA virus of the Flaviviridae family. Like other arboviruses (e.g., St. Louis Encephalitis, Dengue Fever, and Yellow Fever), its main route of transmission to humans is through mosquitoes (primarily culex species) that have acquired the virus from infected birds. A single elevated WNV result, including IgM that may persist for many months, could represent past infection with WNV or infection with another flavivirus including Dengue and St. Louis Encephalitis. Diagnosis of suspected WNV infection is confirmed by isolation of WNV or detection of WNV antigen or nucleic acid sequences in clinical samples or detection of WNV-specific IgM in blood or spinal fluid, confirmed with detection of WNV-specific neutralizing antibody in the same or a subsequent sample.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  06/09/2026

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