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Specimen Collection Manual and Test Catalog

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ANAPLASMA PHAGOCYTOPHILUM ANTIBODIES (IGG, IGM) WITH REFLEX

Geisinger Epic Procedure Code:  LAB5246    Geisinger Epic ID:  207689

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum; minimum 0.2 mL



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 7 days. Refrigerated: 14 days. Frozen: 30 days.



TEST DETAILS
CPT code(s):  86666 (x2)
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

If A. phagocytophilum (IgG) is Detected, then A. phagocytophilum (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If A. phagocytophilum (IgM) is Detected, then A. phagocytophilum (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).


Methodology: 
Immunofluorescence Assay
Synonyms: 

Quest test code 16189


Clinical significance: 

Anaplasma phagocytophilum Antibodies (IgG, IgM) with Reflex to Titers - This test is for the detection of IgG and IgM antibodies against Anaplasma phagocytophilum to aid in the diagnosis of Anaplasmosis (human granulocytic anaplasmosis). Anaplasmosis is a tickborne disease caused by transmission of the bacteria via the bite of an infected tick. It is most common in the Northeastern and upper Midwestern United States during warmer months.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  03/17/2026

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