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Specimen Collection Manual and Test Catalog

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IONIZED CALCIUM, CITRATED ANTICOAGULATION (NEPHROLOGY CRRT RESTRICTED)

Geisinger Epic Procedure Code:  LAB2551    Geisinger Epic ID:  23549

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

Capped, spun 3.5 mL gold-top tube serum separator tube; minimum 1 mL>


Special notes: 

Only for continuous renal replacement therapy (CRRT) patients. Draw post filter.



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge at 1100-2000 x g for 10 minutes at room temperature. Specimen must be spun within 3 hours of collection. Do not uncap or aliquot.


Transport temperature: 

Refrigerated.


Specimen stability: 

Unopened, centrifuged SST tube: stable 3 days refrigerated. 
Unspun and unopened in SST tube: stable 3 hours at room temperature or refrigerated.


Rejection criteria: 

Stability limits exceeded.



TEST DETAILS
Reference interval: 

0.25 - 0.50 mmol/L.


CPT code(s):  82330
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Potentiometric
Synonyms: 

CITCAI, POST FILTER IONIZED CALCIUM


Clinical significance: 

Used to monitor the citrate anticoagulant used during continuous renal replacement therapy (CRRT). Measures the bioavailable calcium present.


Doctoral Director(s): 
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Sheng-Ying (Margaret) Lo, PhD, DABCC
Benjamin Andress, PhD, DABCC
Review Date:  02/09/2026

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