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Specimen Collection Manual and Test Catalog

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COXSACKIE A ANTIBODIES, SERUM

Geisinger Epic Procedure Code:  LAB2088    Geisinger Epic ID:  21444

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

2 mL aliquot of serum; minimum 1 mL.


Special notes: 

Serum separator tubes not acceptable.



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge 10 minutes at 3000 rpm.


Transport temperature: 

Refrigerated.


Specimen stability: 

Room Temperature: 7 days. Refrigerated: 14 days. Frozen: 30 days.


Rejection criteria: 

Specimen collected in serum separator tube.



TEST DETAILS
CPT code(s):  86658 x6
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Coxsackie Antibodies A2, A4, A7, A9, A10, A16.


Methodology: 
Complement Fixation
Synonyms: 

COXSAC, Quest test code 37477


Clinical significance: 

Panel currently includes testing against A-2, 4, 7, 9, 10, and 16 antigens. Although there is cross-reactivity among the enteroviruses by CF, most healthy people do not have titers >1:8. Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  12/16/2024

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