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Specimen Collection Manual and Test Catalog

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CARDIOLIPIN IGA ANTIBODY

Geisinger Epic Procedure Code:  LAB1942    Geisinger Epic ID:  26876

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.5 mL serum; minimum 0.2 mL.



SPECIMEN PROCESSING
Processing instructions: 

Allow serum to clot. Centrifuge and submit 0.5 mL serum.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.


Rejection criteria: 

Specimen stability exceeded; specimen grossly hemolyzed.



TEST DETAILS
Reference interval: 

Negative <14 APL-U/mL


Interpretation guide: 

Negative <14 APL-U/mL 
Equivocal 14-20 APL-U/mL 
Positive >20 APL-U/mL 


CPT code(s):  86147
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Cardiolipin IgA antibody.


Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

CARDA, Cardiolipin antibody IgA, Antiphospholipid IgA antibody, ACA IgA antibody, ACL IgA antibody, Anticardiolipin IgA AB


Clinical significance: 

The presence of cardiolipin antibodies when used in conjunction with clinical findings and other laboratory tests can aid in assessing the risk of thromboembolic disease in patients with systemic lupus erythematosus (SLE) or primary anti-phospholipid syndrome (APS).


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  01/28/2025

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