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Specimen Collection Manual and Test Catalog

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BUPROPION AND METABOLITE, SERUM/PLASMA

Geisinger Epic Procedure Code:  LAB1898    Geisinger Epic ID:  45789

SPECIMEN COLLECTION
Specimen type: 

Serum or plasma


Preferred collection container: 
Specimen required: 

1 mL aliquot of serum or plasma; minimum 0.4 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot.


Special notes: 

Do not use serum separator tube (SST). Collect as trough prior to next dose.



SPECIMEN PROCESSING
Processing instructions: 

Allow blood to clot. Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic, screw-capped vial(s). Freeze and ship frozen. Specimens must be kept frozen. If specimens are not kept frozen, this may cause lower or negative result values.


Transport temperature: 

Frozen.


Specimen stability: 

Frozen: 1 month (-20°C).


Rejection criteria: 

Room temperature and refrigerated specimens unstable and will be rejected. Serum separator tubes not acceptable.



TEST DETAILS
Reference interval: 

Included in report.


CPT code(s):  80338
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Bupropion (Wellbutrin) and hydroxybupropion.


Methodology: 
Chromatography/Mass Spectrometry
Synonyms: 

WELLBUTRIN, BUPROPRION, MASS SPEC QNT, Quest test code 8592, BUP


Clinical significance: 

Bupropion is an antidepressant for treating mental depression. Monitoring its level is important to optimize therapy, to avoid toxicity and to assure compliance.


Review Date:  11/12/2024

Performing Locations