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Specimen Collection Manual and Test Catalog

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ALLERGEN NORTHEAST REGIONAL IGE PROFILE

Geisinger Epic Procedure Code:  LAB1651    Geisinger Epic ID:  21439

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

One (1) full 3.5 mL gold-top serum separator tube. Aliquot also acceptable (1.5 mL minimum).



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and submit one (1) full 3.5 mL gold-top serum separator tube. Aliquot also acceptable (1.5 mL minimum).


Transport temperature: 

Refrigerated.


Specimen stability: 

Stable seven (7) days at 2-8°C or six (6) months at -20°C.


Rejection criteria: 

Specimen will be rejected if stability limit has been exceeded or if specimen is hemolyzed, lipemic or icteric.



TEST DETAILS
Interpretation guide: 

<0.10 kUa/L - Class 0 Allergen: Absence of Allergen Specific IgE 
0.10-0.34 kUa/L - Class 0/1 Allergen: Low Level of Allergen Specific IgE 
0.35-0.69 kUa/L - Class 1 Allergen: Low Level of Allergen Specific IgE 
0.70-3.49 kUa/L - Class 2 Allergen: Moderate Level of Allergen Specific IgE 
3.50-17.49 kUa/L - Class 3 Allergen: High Level of Allergen Specific IgE 
17.5-49.99 kUa/L - Class 4 Allergen: Very High Level of Allergen Specific IgE
50.0-99.99 kUa/L - Class 5 Allergen: Very High Level of Allergen Specific IgE
>=100 kUa/L - Class 6 Allergen: Very High Level of Allergen Specific IgE


Additional information: 
CPT code(s):  86003 x28
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Immunoglobulin E value and class for the following 28 antigens: June grass (G8), timothy (G6), common ragweed (W1), pigweed (W14), oak (T7), elm (T8), mite-Farinae (D2), mite-Pteronyssinus (D1), Alternaria (M6), cat epithelium/dander (E1), dog epithelium (E2), dog dander (E5), Cladosporum (M2), lamb's quarters (W10), Bermuda grass (G2), Penicillin Notatum (M1), Aspergillus (M3), Helminthosporium (M8), Pullularia (M12), Acremonium Kiliense (M202), Box Elder Maple (T1), Birch (T3), Walnut tree (T10), Cottonwood (T14), White Ash (T15), Pecan Hickory (T22), Mugwork (W6), English Plantain (W9), Cocklebur (W13), Sheep Sorrel (W18).


Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

NERAST, NE RAST, NE REGIONAL RAST, NE REGIONAL ALLERGY PANEL


Clinical significance: 

Many allergies are mediated by immunoglobulins of the IgE class. In vitro allergen-specific IgE tests can help the physician identify the allergen (or allergens) to which an individual is sensitive.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  12/12/2024

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