Specimen Collection Manual and Test Catalog
EBV VIRAL CAPSID ANTIGEN IGG ANTIBODY
Geisinger Epic Procedure Code: LAB2230 Geisinger Epic ID: 14931Serum
0.5 mL serum; minimum 0.2 mL
Allow to clot. Centrifuge and submit 0.5 mL serum.
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Room temperature: 8 hours. 2-8°C: 96 hours. Frozen: 6 months
Specimen stability exceeded; specimen grossly hemolyzed.
| Result | Interpretation |
| Negative | Absence of detectable VCA IgG antibodies. If exposure to Epstein-Barr virus is suspected despite a negative finding, a second sample should be collected and tested no less than one to two weeks later. |
| Equivocal | Suggest a second sample be collected and tested one to two weeks later. |
| Positive | Presence of detectable VCA IgG antibodies. A positive result indicates current or past exposure to Epstein-Barr virus. |
This test is for the qualitative determination of IgG antibodies to EBV VCA.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Antibody detection to EBVCA IgG.
EB-VCA IgG, EBV IGG AB, Epstein Barr IgG Antibody, Epstein Barr IgG antibodies to viral capsid
Epstein-Barr virus (EBV) is responsible for infectious mononucleosis (IM) and has also been implicated in Burkitt's lymphoma and nasopharyngeal carcinoma. EBV-VCA IgG antibodies appear at clinical onset of IM and generally peak after 10 weeks. IgG antibodies to EBV-VCA persist through life and by themselves are not indicative of a current infection.
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM