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Specimen Collection Manual and Test Catalog

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RICKETTSIA ANTIBODY PANEL WITH REFLEX TO TITERS

Geisinger Epic Procedure Code:  LAB3010    Geisinger Epic ID:  35221

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
3.5 mL gold-top (serum separator) tube
Specimen required: 

1.0 mL aliquot of serum; minimum 0.4 mL.



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge 10 minutes at 3000 rpm.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 7 days. Refrigerated: 14 days. Frozen: 30 days.


Rejection criteria: 

Gross hemolysis, gross lipemia, microbial contamination may interfere.



TEST DETAILS
Reference interval: 
 ScreenTiter
RMSF IgGNot detected<1:64
RMSF IgMNot detected<1:64
R. typhi IgGNot detected<1:64
R. typhi IgMNot detected<1:64

CPT code(s):  86757 x 4
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers; Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers. If Rickettsia (RMSF) screen is detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed). If Rickettsia (Typhus Fever) screen is detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).


Methodology: 
Immunofluorescence Assay
Synonyms: 

Rocky Mountain Spotted Fever, Quest test code 37507, RCKTAT


Clinical significance: 

Antigen-specific IgG and IgM titers allow rapid diagnosis of infection by organisms within either of the two major groups of Rickettsia. The spotted fever group includes R. rickettsia (Rocky Mountain Spotted Fever) and R. akari (Rickettsial pox). The typhus group includes R. typhi (endemic/maurine typhus) and R. prowazeki (epidemic typhus).


Review Date:  11/21/2024

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