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Specimen Collection Manual and Test Catalog

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LACTATE DEHYDROGENASE ISOENZYME PANEL

Geisinger Epic Procedure Code:  LAB2593    Geisinger Epic ID:  18742

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

2 mL aliquot of serum


Special notes: 

Specimens cannot be shared.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge serum specimens within 1 hour of collection, transfer serum to a clean, plastic, screw-capped vial(s) and transport at room temperature to the laboratory. Specimens cannot be shared.


Transport temperature: 

Room temperature.


Specimen stability: 

Room Temperature: 7 days. Refrigerated: Unacceptable. Frozen: Unacceptable.


Rejection criteria: 

Hemolysis. Frozen or refrigerated specimen.



TEST DETAILS
CPT code(s):  83615, 83625
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Lactate Dehydrogenase (LD) Isoenzymes


Methodology: 
Electrophoresis
Spectrophotometric (Colorimetric)
Synonyms: 

LDHISO, Quest test code 4411


Clinical significance: 

Lactate dehydrogenase (LD) is present in many different organs and tissues such as liver, heart, muscles, kidney, lungs and blood. The usual designation of isoenzymes is LD-I, LD-II, LD-III, LD-IV and LD-V. LD isoenzymes tissue specificity is derived from the fact that LD subunits are synthesized in well-defined ratios and could be used in investigating unexplained causes of Total LD elevations and detection of macro-LD. Do not use LD isoenzymes to detect myocardial injury.


Review Date:  12/12/2024

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