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Specimen Collection Manual and Test Catalog

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SERTRALINE & DESMETHYLSERTRALINE, SERUM/PLASMA

Geisinger Epic Procedure Code:  LAB3049    Geisinger Epic ID:  19193

SPECIMEN COLLECTION
Specimen type: 

Serum or plasma


Preferred collection container: 
Specimen required: 

1 mL serum collected in a red-top tube (no gel) OR 1 mL plasma collected in EDTA (lavender-top) tube or EDTA (pink-top) tube; minimum 0.4 mL.


Special notes: 

Serum separator and plasma separator tubes not acceptable.



SPECIMEN PROCESSING
Processing instructions: 

Serum: Allow to clot. Serum and plasma: Centrifuge.


Transport temperature: 

Room temperature.


Specimen stability: 

Room Temperature: 14 days. Refrigerated: 30 days. Frozen: 30 days.


Rejection criteria: 

Specimen collected in serum or plasma separator tube (SST or PST).



TEST DETAILS
CPT code(s):  80299
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Sertraline (Zoloft® ) is a psychiatric drug indicated for the treatment of major depression and obsessive-compulsive disorders. Its clinical efficacy is similar to that of the traditional antidepressants but are thought to be mediated through inhibition of serotonin reuptake in the brain.


Methodology: 
HPLC-MS/MS
Synonyms: 

SERT, Zoloft, Quest test code 8871


Doctoral Director(s): 
Randin Nelson MD
Review Date:  03/02/2026

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