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Specimen Collection Manual and Test Catalog

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URINE IMMUNOFIXATION, BENCE JONES PROTEIN, RANDOM URINE

Geisinger Epic Procedure Code:  LAB3223    Geisinger Epic ID:  34232

SPECIMEN COLLECTION
Specimen type: 

Random urine.


Preferred collection container: 
Specimen required: 

15 mL aliquot AND 5 mL aliquot of urine; minimum 10 mL and 2 mL, respectively.



SPECIMEN PROCESSING
Processing instructions: 

Do not centrifuge.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 8 hours. 2-8°C: 72 hours. Frozen: 6 months.


Rejection criteria: 

Specimen stability exceeded.



TEST DETAILS
Reference interval: 

Not detected.


CPT code(s):  86335
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Urine immunofixation with interpretation.


Methodology: 
Immunofixation
Synonyms: 

Urine immunoelectrophoresis, Urine immunofixation, UIFE, UIEP, BJP, Urine (random) immunofixation, BJPRD


Clinical significance: 

Serum and urine immunofixation are primarily used to aid in the detection of monoclonal gammopathies. Monoclonal gammopathies have association with diseases such as multiple myeloma, lymphomas, leukemia, amyloidosis and Waldenstrom's macroglobulinemia.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  12/12/2024

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