Specimen Collection Manual and Test Catalog
ALDOSTERONE/PLASMA RENIN ACTIVITY RATIO, LC/MS/MS
Geisinger Epic Procedure Code: LAB1542 Geisinger Epic ID: 26816SPECIMEN COLLECTION
Specimen type:
Plasma
Preferred collection container:
Alternate collection container:
6 mL pink-top K2 EDTA tube
Specimen required:
1.8 mL aliquot plasma; minimum 0.8 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot.
Patient preparation:
Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.
SPECIMEN PROCESSING
Processing instructions:
Centrifuge and aliquot.
Transport temperature:
Frozen.
Specimen stability:
Room temperature: 24 hours. Refrigerated: 24 hours. Frozen: 28 days.
Rejection criteria:
Moderate to gross hemolysis • Plasma collected in a plasma separator tube (PST) • Received thawed.
TEST DETAILS
CPT code(s):
82088, 84244
Note: The billing party has sole responsibility for CPT coding. Any
questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Aldosterone, plasma renin activity.
Methodology:
Chromatography/Mass Spectrometry
Synonyms:
ARENR, Aldosterone renin ratio, Quest test code 16845
Clinical significance:
The aldosterone-renin ratio is used to screen for primary aldosteronism.
Doctoral Director(s):
Review Date:
08/11/2026
Randin Nelson MD
Performing Locations