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Specimen Collection Manual and Test Catalog

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MYELIN BASIC PROTEIN, CSF

Geisinger Epic Procedure Code:  LAB2728    Geisinger Epic ID:  15071

SPECIMEN COLLECTION
Specimen type: 

Cerebrospinal fluid


Preferred collection container: 
Specimen required: 

1.2 mL aliquot of CSF; minimum 0.5 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot.



SPECIMEN PROCESSING
Transport temperature: 

Frozen (preferred). Room temperature or refrigerated specimen also acceptable.


Specimen stability: 

Room Temperature: 1 week. Refrigerated: 2 weeks. Frozen: 21 days.


Rejection criteria: 

Stability limits exceeded. Xanthochromia. RBCs. Hemolysis.



TEST DETAILS
CPT code(s):  83873
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Concentration of myelin basic protein (MBP).


Methodology: 
Radioimmunoassay (RIA)
Synonyms: 

MBP; Myelin basic protein, CSF, MBPCSF, Quest test code 663


Clinical significance: 

The concentration of MBP is often increased in patients with demyelinating diseases such as multiple sclerosis and may be increased in patients with head injury, CNS trauma, tumor, stroke, and viral encephalitis.


Review Date:  12/19/2024

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