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Specimen Collection Manual and Test Catalog

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GLIADIN (DEAMIDATED) IGA AND IGG ANTIBODIES

Geisinger Epic Procedure Code:  LAB2355    Geisinger Epic ID:  17733

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.5 mL serum; minimum 0.2 mL



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and submit 0.5 mL serum.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.


Rejection criteria: 

Specimen stability exceeded; specimen grossly hemolyzed.



TEST DETAILS
Reference interval: 

Negative <7 U/mL


Interpretation guide: 

Negative <7 U/mL 
Equivocal 7-10 U/mL 
Positive >10 U/mL


CPT code(s):  86258 x2
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Deamidated Gliadin IgG, Deamidated Gliadin IgA antibody.


Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

Gliadin Antibody Panel, GLIAB, DGPAG, Celiac, Deamidated Gliadin Peptide Antibody Panel, Gliadin DGP Antibody Panel


Clinical significance: 

Both Gliadin IgA and IgG antibodies are detected in patients with gluten-sensitive enteropathies such as celiac disease and dermatitis herpetiformis.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  12/23/2024

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