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Geisinger Medical Laboratories Test Catalog
THYROGLOBULIN ANTIBODY |
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Geisinger Epic Procedure Code: LAB3158
Geisinger Epic ID: 45852
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SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
Gold-top (serum separator) microcollection tube
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
One (1) full 3.5 mL gold-top serum separator tube. Aliquot also acceptable (0.5 mL minimum). | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow serum to clot. Centrifuge to separate serum within 2 hours of collection. | |
Transport temperature: |
Refrigerated. Frozen acceptable but not preferred. | |
Specimen stability: |
Refrigerated: 3 days. Frozen: 1 month. | |
Rejection criteria: |
Stability limit exceeded. | |
TEST DETAILS |
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Reference interval: |
Less than 115 IU/mL. | |
CPT code(s): |
86800 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Thyroglobulin autoantibody value. | |
Methodology: |
Chemiluminescence Immunoassay |
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Synonyms: |
Thyroglobulin antibody TRYGAB
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Clinical significance: |
Autoantibodies to thyroglobulin (TG autoantodies) are often present in patients with autoimmune thyroid disease. Approximately 10 percent of healthy individuals have TG autoantibodies at low levels; higer concentrations are found in 30 and 85 percent of patients with Graves' disease and Hashimoto's thyroiditis, respectively. TG autoantibody measurements are most useful for evaluating samples submitted for thyroglobulin measurements because TG autoantibodies can interfere with both competitive immunoassays and immunometric assays for thyroglobulin. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM Sheng-Ying (Margaret) Lo, PhD, DABCC |
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| Review Date: | 12/14/2022 | |