Geisinger Medical Laboratories Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

EBV NUCLEAR ANTIGEN IGG ANTIBODY

Geisinger Epic Procedure Code: LAB2232             Geisinger Epic ID: 7431
       

SPECIMEN COLLECTION
Specimen type:
 Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL
SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
 Refrigerated (preferred). Room temperature (stable 8 hours) or frozen specimen also acceptable.
Specimen stability:
 Room temperature: 8 hours. 2-8°C: 96 hours. Frozen: 6 months
Rejection criteria:
 Specimen stability exceeded; specimen grossly hemolyzed.
TEST DETAILS
Interpretation guide:
Result
Interpretation
Negative Absence of detectable EBNA IgG antibodies. A negative result generally excludes past EBV infection. If exposure to Epstein-Barr virus is suspected despite a negative finding, a second sample should be collected and tested no less than one to two weeks later.
Equivocal Suggest a second sample be collected and tested one to two weeks later.
Positive Presence of detectable EBNA IgG antibodies. A positive result is indicative of past infection.
CPT code(s):
 86664
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
 ualitativ
Methodology:
Chemiluminescence
Synonyms:
EBNA, Epstein Barr IgG antibody to nuclear antigens
Epstein Barr Nuclear Antigen, Epstein Barr Virus
EBV-EBNA, EBNAAB, EBV Serology, EBNA, EBV Antibody
EBNA IgG Antibody, Epstein Barr Nuclear Antigen IgG
Clinical significance:
Epstein-Barr virus (EBV) is responsible for infectious mononucleosis (IM) and has also been implicated in Burkitt's lymphoma and nasopharyngeal carcinoma. EBV-NA (Epstein-Barr virus nuclear antigen) IgG antibodies appear during the convalescent phase of IM and remain present throughout life. A positive EBV-NA IgG antibody in a healthy individual indicates past immunological exposure to EBV.
Doctoral Director(s:)
Hoi-Ying Elsie Yu PhD, DABCC, FADLM    
Review Date: 12/13/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Five days per week, 1st shift.
Performed STAT? No
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