Dr. Marlen Menlyadiev

Marlen Menlyadiev, PhD, NRCC
Associate Director, Clinical Chemistry

100 North Academy Avenue
Danville, PA 17822-1930

800-695-6491

Dr. Menlyadiev is an associate of Geisinger Medical Laboratories at Geisinger Medical Center, where he serves as the Associate Director of Clinical Chemistry.  He is also an assistant professor at Geisinger Commonwealth School of Medicine.

Education:

Dr. Menlyadiev received his PhD in Analytical Chemistry at the New Mexico State University in Las Cruces. He completed a post-doctoral fellowship at the Jet Propulsion Laboratory, California Institute of Technology in Pasadena and a research fellowship at Brigham and Women's Hospital, Harvard Medical School in Boston, Massachusetts. He is a graduate of a Clinical Chemistry fellowship at the University of California, San Diego.

Professional Affiliations:

Association for Diagnostics & Laboratory Medicine (formerly American Association of Clinical Chemistry)
American Society for Mass Spectrometry

Research Interests:

Clinical chemistry. Clinical toxicology and mass spectrometry. Metabolomics and biomarker discovery. Analytical instrumentation for trace analysis. 

Selected Awards:

Discover Brigham Research Excellence Award, Brigham and Women’s Hospital, Harvard Medical School, November 2019, for outstanding contributions to research at Brigham and Women’s Hospital

2022 Trainee Educational Grant, Association for Mass Spectrometry and Advances in the Clinical Lab (MSACL), April 2022, conference travel award

2023 Young Investigator Grant, Association for Mass Spectrometry and Advances in the Clinical Lab (MSACL), April 2023, conference travel award

Recent Academic Activity

Publications in Peer-Reviewed Journals:

Menlyadiev, M., Henderson, B., Zhong, F., Lin, Y., & Kanik, I. (2019). Extraction of amino acids using supercritical carbon dioxide for in situ astrobiological applications. International Journal of Astrobiology, 18(2), 102-111.

Lund K, Menlyadiev M, Lee K, Kelner MJ, Fitzgerald RL, Suhandynata RT. Comparison of two highly sensitive benzodiazepine immunoassay lab developed tests for urine drug testing in clinical specimens. J Mass Spectrom Adv Clin Lab. 2023 Mar 1;28:91-98.

Menlyadiev M, Suhandynata RT, Lund K, Kelner MJ, Fitzgerald RL. Evaluating the performance of the Roche FEN2 fentanyl immunoassay and its clinical implementation: The role of LDT-based mass spectrometry testing. J Mass Spectrom Adv Clin Lab. 2023 Mar 9;28:105-113.

Abstracts, Posters, and Invited Presentations:

Menlyadiev, M.R.; Fowler, P. E.; Schmidt, H.; Lukow, S.R.; Eiceman, G.A. “Improved Selectivity in Narcotics Detection by Tandem DMS through Combination of Chemical Modifiers and Ion-Molecule Reactions” 66th ASMS Conference on Mass Spectrometry and Allied Topics, San Diego, CA, June 3-8, 2018.

Romanov, V.; Menlyadiev, M.R.; Platow, W.; Lynch, E.; Lukow S.R. “Rapid Detection of Fentanyl and Fentanyl Analogs Using Hybrid ITMS-MS System” 66th ASMS Conference on Mass Spectrometry and Allied Topics, San Diego, CA, June 3-8, 2018.

Menlyadiev, M.R.; So, R.; Kristal, B.S..; Duffy, J.F.; Czeiser, C.A. “Potential of breath metabolomics for the assessment of sleep deficiency and circadian timing” Discover Brigham 2019, Boston, MA, November 7, 2019.

Menlyadiev, M.R.; So, R.; Kristal, B.S..; Duffy, J.F.; Czeiser, C.A. “Real-time breath metabolomics for circadian time determination” Harvard Medical School/Brigham and Women’s Hospital’s 19th Sleep and Health Benefit Meeting, Boston, MA, December 7, 2020.

Williams G. R., Menlyadiev M. R., Bachmann L. M., Tolan N. V. “High-Dose Vitamin C Therapy: A Cause for Concern with Routine Clinical Testing” 2020 AACC Annual Scientific Meeting & Clinical Lab Expo, Chicago, IL, December 13-17, 2020.

Suhandynata R. T., Koswatta P., Lund K., Menlyadiev M., Sreenivasan U., Lima H.M., Fitzgerald R.L. “Get Your Reference Right!: Synthesis, Certification, and Confirmation of the First Reference Material for (-)-trans-11-nor-9-Carboxy-Δ9-THC beta-d-glucuronide”  MSACL 2022 US: 12th Annual Conference and Exhibits, Monterey, CA, April 5-8, 2022.

Menlyadiev M.R., Lund K., Suhandynata R. T., Kelner M.J. Fitzgerald R. L. “Comparison of the new Roche FEN2 and the Thermo DRI fentanyl immunoassays”. 2022 AACC Annual Scientific Meeting & Clinical Lab Expo, Chicago, IL, December 13-17, 2020.

Menlyadiev M.R., Suhandynata R.T., Lund K., Kelner M.J., Alabi A., Fitzgerald R.L. “Using LC-MS/MS LDT to determine fentanyl prevalence and evaluate the FEN2 immunoassay’s real-world clinical performance in tertiary care settings”. MSACL 2023 US: 13th Annual Conference and Exhibits. Monterey, CA, April 2-7, 2023.

Menlyadiev M. Fentanyl Testing in Clinical Laboratory: Past, Present, and Future. Roundtable presentation at 2023 ADLM (formerly AACC) Annual Scientific Meeting & Clinical Lab Expo. Anaheim, CA,, July 22 -27, 2023.

Textbook Chapters:

G.A. Eiceman; Lee, G-I.; Menlyadiev, M.R; Fowler, P.; Pasupuleti, D.; Holopainen, S.; Chiluval, U.; Shokri, H. Tandem mobility spectrometry at ambient pressure. In: Comprehensive Analytical Chemistry, Volume 83. Advances in Ion Mobility-Mass Spectrometry: Fundamentals, Instrumentation and Applications, pp. 23-51, Elsevier, 2019.